Slow phosphor-Y-LAT-ion for TCR ligand discrimination

Enrique Aguado,Mikel M. Arbulo-Echevarria

NATURE IMMUNOLOGY（2019）

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摘要

report sheds new light on the molecular mechanisms responsible for the discrimination of self versus non-self TCR ligands and reveals the crucial role of the kinetics of LAT tyrosine phosphorylation in this.

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关键词

Signal transduction,T-cell receptor,T cells,Biomedicine,general,Immunology,Infectious Diseases

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