An assessment of Oxford Nanopore sequencing for human gut metagenome profiling: A pilot study of head and neck cancer patients

Journal of Microbiological Methods(2019)

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摘要
Gut metagenome profiling using the Oxford Nanopore Technologies (ONT) sequencer was assessed in a pilot-sized study of 10 subjects. The taxonomic abundance of gut microbiota derived from ONT was comparable with Illumina Technology (IT) for the high-abundance species. IT better detected low-abundance species through amplification, when material was limited.
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关键词
Microbiome,Shotgun metagenome sequencing,Head and neck cancer,Next-generation sequencing,Third-generation sequencing
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