Interneuron dysfunction in epilepsy: An experimental approach using immature brain insults to induce neuronal migration disorders
Epilepsy Research(2019)
摘要
•Insults to the immature developing brain induce intensive neuronal apoptosis.•Tangential neuronal migration and interkinetic nuclear migration are disturbed.•Abnormal mobilization and the altered distribution of interneurons are induced.•Interneurons are vulnerable to excitotoxic brain injury.
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关键词
Interneuron,Epilepsy,Neuronal migration disorder,γ-aminobutyric acid,Epileptogenesis
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