Adaptation of Cupriavidus necator to levulinic acid for enhanced production of P(3HB-co-3HV) copolyesters

•Evolved strains demonstrated better growth in the presence of LA.•Adaptation of C. necator H16 to LA led to higher content of 3HV in P(3HB-co-3HV).•Higher 3HV content was connected with lower crystallinity and lower Tm.•Slightly different adaptation strategies of evolved strains were observed.•PCA has been used for multiparametric analysis of data.