Biological interactions between nanomaterials and placental development and function following oral exposure

•The placenta is an efficient barrier to protect the fetus against nanomaterials.•Nanomaterials accumulate in placental tissue and often experience low clearance.•Nanoplastics’ impact on placental development and function is largely unknown.•Laboratory animal species and gestational age at exposure impact adverse outcome.•Nanomaterial physiochemical properties strongly influence the adverse outcome.