One-pot approach to access 2H-pyran-2-ones bearing an amino group via the Pd-catalyzed Sonogashira coupling of (Z)-3-iodovinylic esters followed by intramolecular iodocyclization

Atef Mayooufi,Moufida Romdhani-Younes,Johan Jacquemin,Jérôme Thibonnet

Tetrahedron Letters（2019）

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摘要

•Palladium catalysis.•Intramolecular iodocyclization.•Threefold couplings.•Inexpensive alcohol solvents.•Good group tolerance chemoselectivity toward 2H-pyran-2-ones.

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关键词

Pyranone,Iodocyclization,Enynoate,One-pot procedure

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