Pediatric Septic Shock Collaborative: Description Of Early Improvement

Purpose: Severe sepsis is a significant source of morbidity and mortality in children. Lack of adherence to evidence based treatment guidelines, including under-recognition and delayed resuscitation, contribute to increased morbidity. Single-site quality improvement (QI) initiatives focused on early recognition and standardized care pathways have improved outcomes including time to interventions, as well as decreased end-organ dysfunction and mortality, but variation in their utilization remains. Methods: The American Academy of Pediatrics Pediatric Septic Shock Collaborative (AAP-PSSC) was a multi-center quality improvement and learning collaborative with 20 participating US pediatric emergency departments (EDs), with …