Morphological quantification of proliferation-to-invasion transition in tumor spheroids.

Yi He,Ling Xiong,Xuejuan Gao,Miaomiao Hai,Yanping Liu,Gao Wang,Guo Chen,Jianwei Shuai,Yang Jiao,Xixiang Zhang,Ruchuan Liu,Liyu Liu

Biochimica et Biophysica Acta (BBA) - General Subjects（2020）

引用 5|浏览24

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摘要

•Proliferation-to-invasion transition model by tumor spheroids in defined conditions•Image-based, automated and quantitative analysis of the morphological transitions•Proposed suitable parameters for well definition of the transition point•Transition point and time provide good assistance for cancer invasion investigation

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关键词

Living-cell device,Tumor spheroids model,Cancer invasion,Image processing,Quantitative analysis,Transition time

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