Observation Versus Immediate Reinduction for Acute Myeloid Leukemia Patients With Indeterminate Day 14 Bone Marrow Results.

Omer Jamy,Charles Bodine,Devi Sampat,Rehan Sarmad,Awal Chadha,Pankit Vachhani,Nikolaos Papadantonakis,Antonio Di Stasi

Clinical Lymphoma Myeloma and Leukemia（2020）

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摘要

Our study did not find a statistically significant difference in the overall response rates or survival outcome measures for patients with AML and indeterminate day 14 bone marrow in the 2 treatment groups. Our findings question the utility of immediate reinduction chemotherapy and raise concern regarding overtreatment in this patient population. Larger studies investigating similar outcomes are warranted to validate our clinical findings.

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关键词

Acute leukemia,Day 14 marrow biopsy,Indeterminate bone marrow,Residual disease,Treatment

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