Genetic diversity and geographical distribution of the Siberian subtype of the tick-borne encephalitis virus.

S E Tkachev, I V Babkin, G S Chicherina,I V Kozlova, M M Verkhozina,T V Demina, O V Lisak,E K Doroshchenko,Yu P Dzhioev, O V Suntsova,P S Belokopytova,A Yu Tikunov, Yu S Savinova,A I Paramonov,V V Glupov, V I Zlobin,N V Tikunova

Ticks and Tick-borne Diseases（2020）

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摘要

•Tick-borne encephalitis virus, Siberian subtype (TBEV-Sib) exhibits high diversity.•A novel Bosnia lineage was described within TBEV-Sib in addition to known lineages.•Each TBEV-Sib lineage has a certain pattern of geographic distribution.•TBEV-Sib spread across Eurasia was not linear and included multiple introductions.•Average substitutions rate in TBEV-Sib ORFs was 3.0 × 10-5 substitutions/site/year.

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关键词

Tick-borne encephalitis virus,Siberian subtype,Genetic lineages,Genetic diversity,Phylogeography

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