Polymer-functionalized mesoporous carbon nanoparticles on overcoming multiple barriers and improving oral bioavailability of Probucol

Hongyan Lu, Guangzhao Yang,Fu Ran,Tianbin Gao,Changshan Sun,Qinfu Zhao,Siling Wang

Carbohydrate Polymers（2020）

引用 22|浏览6

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摘要

•Polymer-modified MCNs to overcome mucous and epithelial barriers is rarely reported.•Cellular uptake of MCNs is quantified by UV spectrophotometry.•Polymer-modified MCNs could trace the MCNs in vivo and control the drug release.

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关键词

Mesoporous carbon,Nanoparticles,Chitosan,HPMA copolymers,Absorption barriers,Oral bioavailability

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