Identification of the epitope in human poliovirus type 1 Sabin strain recognized by the monoclonal antibody 1G10 using mimotope strategy.

•A novel strategy named “mimotope” was offered to achieve the identification of epitopes recognized by PV mAbs.•From mimotope strategy through bio-panning and “in silico” prediction by bioinformatics tools, a target region of epitope recognized by mAb 1G10.•We propose 1G10 could be used for in-house potency ELISA kit or developing national and international standards in the future.