Magnetic bead-gold nanoparticle hybrids probe based on optically countable gold nanoparticles with dark-field microscope for T4 polynucleotide kinase activity assay

Yuanfang Zhao
Yuanfang Zhao
Chunyan Tan
Chunyan Tan
Shuqing Sun
Shuqing Sun
Ying Tan
Ying Tan

Biosensors and Bioelectronics, pp. 1119362019.

Cited by: 0|Bibtex|Views1|DOI:https://doi.org/10.1016/j.bios.2019.111936
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Other Links: pubmed.ncbi.nlm.nih.gov|academic.microsoft.com|www.sciencedirect.com

Abstract:

T4 polynucleotide kinase (T4 PNK) plays an essential role in DNA phosphorylation during the DNA repair process. Therefore, the sensitive, selective and convenient detection of T4 PNK activity is of great significance. In this work, we proposed a sensitive non-amplification strategy for the sensing of T4 PNK activity via dark field microsc...More

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