Effects of the multisensory rehabilitation product for home-based hand training after stroke on cortical activation by using NIRS methods.

•NIRS was designed to detect effect of stimulation on cortical activation response.•Multisensory environment can induce cortical activation in most brain regions.•Multisensory stimuli are more beneficial to neural activities and cognitive control.•Activation of the motor cortex is closely related to the cognitive performance.