Reply to Rockey et al., "Genomics and Chlamydial Persistence In Vivo ".
MBIO(2019)
摘要
We read with interest the recent paper by Somboonna and colleagues, addressing changes to tryptophan synthase in a single Chlamydia trachomatis strain that had an aberrant growth phenotype in vitro (1). This strain was isolated four times, over 4 years, from a patient who was apparently persistently infected. This strain was highly related to a serovar F strain isolated previously in their clinical setting. The authors use these strains to defend an association between in vivo persistence and a particular mutation at the 3′ end of the …
更多查看译文
关键词
Chlamydia trachomatis,indole,interferon gamma,sexually transmitted diseases,trpA,tryptophan synthase
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要