Equations to Predict Antimicrobial MICs in Neisseria Gonorrhoeae Using Molecular Antimicrobial Resistance Determinants
Antimicrobial agents and chemotherapy(2019)
摘要
The emergence of Neisseria gonorrhoeae strains that are resistant to azithromycin and extended-spectrum cephalosporins represents a public health threat, that of untreatable gonorrhea infections. Multivariate regression modeling was used to determine the contributions of molecular antimicrobial resistance determinants to the overall antimicrobial MICs for ceftriaxone, cefixime, azithromycin, tetracycline, ciprofloxacin, and penicillin.
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关键词
MIC,Neisseria gonorrhoeae,antimicrobial resistance,molecular analysis,whole-genome sequencing
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