Multi-objective optimization genetic algorithm for multi-point light focusing in wavefront shaping.

We introduce a new multi-objective genetic algorithm for wavefront shaping and realize controllable multi-point light focusing through scattering medium. Different from previous single-objective optimization genetic algorithms, our algorithm named Non-dominated Sorting Genetic Algorithm II based on hybrid optimization scheme (NSGA2-H) can make all focus points have uniform intensity while ensuring that their enhancement is as high as possible. We demonstrate the characteristics of NSGA2-H through simulations and experiments in amplitude optimization, analyze its optimization mechanisms and show its powerful optical control capability in uniform intensity focusing and even in customizable intensity focusing. This research will be expected to further promote future practical applications based on multi-point focusing of wavefront shaping, especially in optical trapping and optogenetics. (C) 2019 Optical Society of America under the terms of the OSA Open Access Publishing Agreement