Advances in amide and thioamide assisted C(sp3)-H functionalization

Tetrahedron Letters（2019）

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摘要

•Directed CH functionalization is emergent as a powerful tool in organic synthesis.•Amides and thioamides are versatile directing groups for C(sp3)H activation.•Cyclometalation and amidyl radical based C(sp3)H functionalizations are reviewed.•Success stories in amide directed remote C(sp3)H functionalizations are highlighted.

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关键词

CH functionalization,Amide,Thioamide,Directed,C(sp3)H activation

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