Fungal Infections In Chronic Lymphocytic Leukemia Before And After Treatment

BLOOD(2019)

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摘要
Background: Patients with Chronic Lymphocytic Leukemia (CLL) are susceptible to infections due to impaired immunity, from both complications of disease and treatments. Specific treatments such as fludarabine or rituximab are incorporated in chemotherapy regimens for CLL and cause lymphocyte depletion and impaired humoral immunity, resulting in increased risk of fungal infections. The aim of this study is to explore the incidence rates of fungal infections in patients before and after treatment for CLL.
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