Design, synthesis and bioactivity evaluation of coumarin-chalcone hybrids as potential anticancer agents.
Bioorganic Chemistry（2020）
摘要
Fluorescent coumarin-chalcone hybrid Xn-2 inhibited TrxR activaty to exert antitumor activity.
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关键词
Thioredoxin reductases (TrxRs),Xanthohumol (Xn),Hybrids,Fluorescence,Mitochondrial apoptosis,Cancer therapy
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