Expression of programmed death ligand 1 (PD-L1) is associated with metastasis and differentiation in gastric cancer.

Peng-Xing He,Zhi-Lu Ma,Huan Han,Xu-Yang Zhang,Sheng-Hui Niu,Lin-Na Du,Yi-Chao Zheng,Hong-Min Liu

Life Sciences（2020）

引用 17|浏览21

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摘要

•PD-L1 expression is significantly lower in GC than that in adjacent normal tissues.•Low PD-L1 decreases E-cadherin expression, promotes cell migration and wound repair ability.•ATRA up-regulates the expression of PD-L1 and E-cadherin.

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关键词

Gastric cancer (GC),Programmed death ligand 1(PD-L1),Metastasis,Differentiation,All-trans retinoic acid (ATRA)

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