Direct photochemical cross-coupling between aliphatic acids and BF 3 K salts.

We describe a novel photoredox hetero-coupling reaction of two C (sp(3)) radicals from aliphatic acids or BF3K salts. The kinetic differences in radical persistence provide cross-selectivity, using an organic photoredox catalyst and an oxidant with visible light. This method exhibits broad scope, including several examples constructing sterically hindered C(sp(3))-C(sp(3)) bonds.