Impact of proprotein convertase subtilisin/kexin type 9 inhibition with evolocumab on the postprandial responses of triglyceride-rich lipoproteins in type II diabetic subjects.

Journal of Clinical Lipidology(2020)

引用 23|浏览78
暂无评分
摘要
•Evolocumab treatment improves postprandial responses of triglyceride-rich lipoproteins in type II diabetics.•Evolocumab treatment decreases remnant lipoproteins as well as small very-low-density lipoprotein and low-density lipoprotein.•This reduces atherosclerotic cardiovascular disease risk as the atherogenic potential of remnants equal that of low-density lipoprotein.•It is important to test postprandial responses when evaluating novel drug therapies.
更多
查看译文
关键词
apoB,Postprandial lipids,Remnant lipoproteins,Apolipoprotein C3,Atherogenic dyslipidemia,De novo lipogenesis,Evolocumab,PCSK9,Liver fat
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要