Dual delivery nanoscale device for miR-451 and adriamycin co-delivery to combat multidrug resistant in bladder cancer.

Shuguang Wei, Jiannan Gao, Maopeng Zhang,Zhongling Dou,Wensheng Li,Leizuo Zhao

Biomedicine & Pharmacotherapy（2020）

引用 20|浏览8

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摘要

•The cancer cell membrane (CM) coated calcium carbonate (CC) nanoparticles was successfully constructed.•The multidrug resistant was reversed by miR-451.•Combination of miR-451 and Adriamycin was proposed to treat bladder cancer.

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关键词

MDR,DDS,CM,CC,P-gp,miRNA,Adr,MTT,AEAPS,MCTS,DLC,HPLC

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