Seasonal expressions of prostaglandin E synthases and receptors in the prostate of the wild ground squirrel (Spermophilus dauricus).

Prostaglandins & Other Lipid Mediators(2020)

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摘要
•The prostate gland of wild ground squirrel produces PGE2 in a seasonal manner.•Seasonal expression of COX-1/2 and PTGES are responsible for PGE2 production.•Epithelial and stromal cells are the sources for PGE2 production.•PGE2 regulates seasonal changes of prostatic function via locally expressed receptors.
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关键词
COX-1,COX-2,PTGES,PGE2 receptors,Prostate,Prostaglandin E2,Wild ground squirrel
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