Effects of sildenafil on inflammatory injury of the lung in sodium taurocholate-induced severe acute pancreatitis rats

Dazhang Fang,Qi Lin,Cheng Wang,Chenlei Zheng,Yonglin Li,Tingting Huang,Fubiao Ni,Zhigang Wu,Bicheng Chen,Linxiao Sun

International Immunopharmacology（2020）

引用 16|浏览6

暂无评分

摘要

•Acute lung injury occurs in sodium taurocholate-induced severe acute pancreatitis.•Sildenafil decreases inflammatory factors, neutrophils and chemokines generation.•Sildenafil could promote proliferation and inhibit apoptosis under SAP condition.•Sildenafil may enhance antioxidant (Nrf2 and HO-1) genes and suppress NF-κb.

查看译文

关键词

Sildenafil,SAP,Lung injury,Inflammation,Nrf2,NF-κb

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要