Activation of AMPK pathway compromises Rab11 downregulation-mediated inhibition of Schwann cell proliferation in a Glut1 and Glut3-dependent manner.

Fan Li,Wei Du,Hui Wang,Song Zhao,Lin Zhu,Jun Hao

Neuroscience Letters（2020）

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摘要

•Rab11 downregulation inhibited the proliferation of rat Schwann cells.•AMPK pathway activation ameliorated Rab11 downregulation-mediated inhibition of rat Schwann cell proliferation.•Rab11 downregulation activated AMPK pathway by reducing Glut1 and Glut3 expression.

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关键词

Rab11,Proliferation,AMPK,Glut1,Glut3,Schwann cells

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