Transient receptor potential vanilloid-3 (TRPV3) channel induces dermal fibrosis via the TRPV3/TSLP/Smad2/3 pathways in dermal fibroblasts.

Journal of Dermatological Science（2020）

引用 28|浏览12

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摘要

•Carvacrol (TRPV3 agonist) increased ECM production.•TRPV3 regulates TSLP/Smad2/3pathways.•TRPV3 inhibits dermal fibrosis by reducing ECM production.

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关键词

Transient receptor potential vanilloid-3,Thymic stromal lymphopoietin,Fibrosis

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