Vaginal dysbiosis associated-bacteria Megasphaera elsdenii and Prevotella timonensis induce immune activation via dendritic cells.

•Megasphaera elsdenii and Prevotella timonensis increased expression of CD80, CD83, and CD86 on dendritic cells.•Megasphaera elsdenii and Prevotella timonensis induced production of pro-inflammatory cytokines by dendritic cells.•Prevotella timonensis-stimulated dendritic cells induced T helper 1 skewing of naïve CD4 + T cells.•Commensal Lactobacillus crispatus did not induce inflammatory immune responses in dendritic cells.