Deoxycholic acid-stimulated macrophage-derived exosomes promote spasmolytic polypeptide-expressing metaplasia in the stomach.

Biochemical and Biophysical Research Communications(2020)

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摘要
•Deoxycholic acid promoted the development of spasmolytic polypeptide-expressing metaplasia in the stomach of mouse.•Macrophage-derived exosomes were internalized by gastric organoid from mouse.•Exosomes promoted the development of spasmolytic polypeptide-expressing metaplasia in gastric organoids.
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关键词
Deoxycholic acid,Macrophages,Exosomes,Gastric organoids,Spasmolytic polypeptide-expressing metaplasia
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