Administration of aspirin tablets using a novel gel-based swallowing aid: an open-label randomised controlled cross-over trial.
BMJ innovations(2019)
摘要
We cannot assume that uncoated aspirin administration with and without gel is bioequivalent. Administration with gel resulted in reduced salicylate levels and therefore increased platelet function. Further research is required to determine the exact reason for this result. The results bring into question current processes for providing marketing authorisation for medical devices which are designed to aid swallowing.
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关键词
aspirin,bioequivalence,dysphagia,platelet function,salicylate levels,swallowing aid
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