Patchy Scotoma Observed In Chorioretinal Patchy Atrophy Of Myopic Macular Degeneration
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE(2020)
摘要
PURPOSE. To investigate the retinal sensitivity of highly myopic eyes with chorioretinal patchy atrophy (PA) using microperimetry.METHODS. Fifty-two eyes of 32 patients with high myopia were prospectively included. Twenty-two eyes of 16 patients had PA lesions; eyes without PA were analyzed as controls. Testing points on microperimetry in eyes with PA were designated as 3 zones: zone 1 as the PA lesion including its borders; zone 2 including testing points adjoining PA; zone 3 including all other testing points.RESULTS. In the PA group, the mean retinal sensitivity in zone 1 was 2.1 +/- 2.8 dB, zone 2 = 8.3 +/- 4.3 dB, and zone 3 = 9.4 +/- 4.1 dB. Sensitivity in zone 1 was significantly reduced than zones 2 and 3 (P < 0.001). The mean retinal sensitivity in the PA group was lower than controls (6.5 +/- 4.3 vs 13.9 +/- 4.1 dB, P < 0.001), and combined zone 2 and 3 in the PA group also presented lower retinal sensitivity (8.8 +/- 4.0 dB).CONCLUSIONS. Eyes with PA generate patchy scotoma in PA lesions and reduced retinal sensitivity in regions beyond atrophic lesion on microperimetry. The presence of PA may be an indicator to reflect both significantly anatomical and functional alterations on myopic macular degeneration.
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关键词
high myopia, patchy atrophy, chorioretinal atrophy, myopic macular degeneration, microperimetry
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