BROWN TUMOR IN A PATIENT WITH RENAL FAILURE AND SECONDARY HYPERPARATHYROIDISM

A 28-year-old woman sought care due to an increase in mandible volume lasting approximately 1 year. The patient had chronic kidney disease caused by Berger disease in childhood, and underwent hemodialysis 3 times a week. An intraoral clinical examination revealed an expansive lesion on the left side of the mandible, causing mobility of the adjacent teeth. The radiographic examination showed a lesion of imprecise borders in the region of the right mandible of approximately 2 cm in size. An incisional biopsy and histologic examination revealed a giant cell lesion. Due to the patient's systemic picture of secondary hyperparathyroidism, the diagnosis is compatible with Brown tumor. After 6 months, she received a kidney transplant and after 6 months of follow-up, the lesion presented with partial healing. However, hyperparathyroidism did not show improvement, and surgery for the removal of parathyroid glands was indicated by the endocrinologist. A 28-year-old woman sought care due to an increase in mandible volume lasting approximately 1 year. The patient had chronic kidney disease caused by Berger disease in childhood, and underwent hemodialysis 3 times a week. An intraoral clinical examination revealed an expansive lesion on the left side of the mandible, causing mobility of the adjacent teeth. The radiographic examination showed a lesion of imprecise borders in the region of the right mandible of approximately 2 cm in size. An incisional biopsy and histologic examination revealed a giant cell lesion. Due to the patient's systemic picture of secondary hyperparathyroidism, the diagnosis is compatible with Brown tumor. After 6 months, she received a kidney transplant and after 6 months of follow-up, the lesion presented with partial healing. However, hyperparathyroidism did not show improvement, and surgery for the removal of parathyroid glands was indicated by the endocrinologist.