What we can learn from a genetic rodent model about autism

Dorit Möhrle,Marta Fernández,Olga Peñagarikano,Andreas Frick,Brian Allman,Susanne Schmid

Neuroscience & Biobehavioral Reviews（2020）

引用 39|浏览23

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摘要

•How core symptoms of autism are modeled in rodents.•Genetic animal models recapitulate specific clusters of symptoms of autism.•They are an excellent tool to study mechanisms and treatments.•We provide an overview which models exhibit what type of autism symptom.

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关键词

Autism spectrum disorder,Genetic,Animal model,Mechanisms,Fragile-X,Cntnap2,Behavioural testing

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