Bicyclic Lactams Derived from Serine or Cysteine and 2-Methylpropanal

Halima Bagum,Bethany R. Shire,Kirsten E. Christensen,Miroslav Genov,Alexander Pretsch,Dagmar Pretsch,Mark G. Moloney

SYNLETT（2020）

引用 3|浏览9

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摘要

Bicyclic lactams may be prepared from serine or cysteine and 2-methylpropanal; the resulting S,N-are more stable than the corresponding O,N-heterocycles but both are synthetic intermediates capable of further elaboration.

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关键词

lactams,antibiotics,cyclisation,heterocycles

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