Bisabolane sesquiterpenes from the leaves of Lindera benzoin reduce prostaglandin E2 formation in A549 cells

Astrid Henz Ryen, Thomas Göls,Julia Steinmetz,Ammar Tahir,Per-Johan Jakobsson,Anders Backlund,Ernst Urban,Sabine Glasl

Phytochemistry Letters（2020）

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摘要

•Three new bisabolane sesquiterpenes were isolated from Lindera benzoin.•Their structure elucidation was achieved via MS and extensive NMR measurements.•Anti-inflammatory properties of the isolated bisabolane sesquiterpenes were studied.•A significant reduction of pro-inflammatory prostaglandin E2 formation in A549 cells was observed.

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关键词

Lindera benzoin,Sesquiterpenes,Structure elucidation,Prostaglandin E2,Anti-inflammatory

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