Single or two drug combination therapy as initial treatment for low risk, gestational trophoblastic neoplasia. A Canadian analysis.

Paul J Hoskins,Nhu Le,Aalok Kumar,Annick Pina,Jeanelle N Sabourin,Hannah Kim,Ray J Osborne

Gynecologic Oncology（2020）

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摘要

•Low risk GTN is curable.•Weekly methotrexaxte is a poor initial choice.•Q2w dactinomycin is a better choice than combination methotrexate/dactinomycin.•If HCG ≥10,000 or prognostic score 5 or 6, then combination is better.

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Gestational Trophoblastic Disease

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