A Digital Twin Feasibility Study (Part I): Non-Deterministic Predictions of Fatigue Life in Aluminum Alloy 7075-T651 Using a Microstructure-based Multi-scale Model

•A multi-scale, non-deterministic fatigue life prediction framework was demonstrated.•Aleatory uncertainty in microstructure is linked to the scatter in short crack growth rates.•Uncertainties obtained from the microscale fatigue model are propagated to the macroscale model.•Uncertainty in the predicted fatigue life is compared to the actual number of cycles to failure.