Novel vanillin derivatives containing a 1,3,4-thiadiazole moiety as potential antibacterial agents.

Qiong Wu, Hui Cai,Ting Yuan,Shaoyuan Li,Xiuhai Gan,Baoan Song

Bioorganic & Medicinal Chemistry Letters（2020）

引用 32|浏览14

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摘要

•Thirty-four novel vanillin derivatives containing 1,3,4-thiadiazole moiety were synthesized.•Compound 29 exhibited remarkable antibacterial activities against Xoo and Xoc.•Compound 29 affected cellular structure and metabolism of Xoo.

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关键词

Vanillin,1,3,4-Thiadiazole,Antibacterial activity,Rice bacterial diseases

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