Relationships of Lipids Profile with Health-Related Quality of Life in Chinese Centenarians

Objectives With the acceleration of the process of aging population, to enjoy a higher health-related quality of life (HRQoL) is the goal of the elderly population and public health. Studies on relationship between HRQoL and lipid profile through a large sample of representative elderly population are scare. Objective This study was conducted to firstly explore the relationships of lipid profile with HRQoL in Chinese centenarian population. Participants A complete sample of 1002 participants aged over 100 years from Hainan province were recruited in the current study. Main measure Questionnaire investigation, physical examination and blood specimen collection were carried out by family survey. The EuroQol-5 Dimensions(EQ-5D, and EQ-VAS were used to assess HRQoL. Results In multivariate linear regression analyses, a significant association was found between EQ-5D and lipid profile, including total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), and similar association was also existed between EQ-VAS and TC, LDL-C HDL-C, after adjustment. The score of EQ-5D and EQ-VAS in male centenarian was higher than that of the female centenarian. Conclusion Lipid profile was positively associated with the HRQoL in Chinese centenarians.