enetic diagnosis and clinical characteristics by etiological classification in early-onset epileptic encephalopathy with burst suppression pattern.

•Precise etiological diagnosis of EOEE-BS may be helpful in identifying clinical features and prognosis.•Molecular etiology may comprise a significant proportion of EOEE-BS, irrespective of structural abnormalities.•Targeted gene sequencing is an effective tool for diagnosing the genetic background of patients with EOEE-BS.•Treatment options can differ depending on the etiological diagnosis, with surgical treatment being a consideration in patients diagnosed with cortical dysplasia regardless of genetic background.