Corrigendum to "the BACE1 Product Sappβ Induces ER Stress and Inflammation and Impairs Insulin Signaling" [metab Clin Exp 85 (2018) 59-75].

The authors have noticed that incorrect GADPH (Fig. 3F), IRS1 and GADPH (Fig. 3H) immnunoblots were inadvertently used when preparing the Figures. These errors have been corrected in the version of Fig. 3 included below. Please note that the mistake does not affect the results or conclusions of this work. The authors would like to apologise for any inconvenience caused. The BACE1 product sAPPβ induces ER stress and inflammation and impairs insulin signalingMetabolism - Clinical and ExperimentalVol. 85Previewβ-secretase/β-site amyloid precursor protein (APP)-cleaving enzyme 1 (BACE1) is a key enzyme involved in Alzheimer's disease that has recently been implicated in insulin-independent glucose uptake in myotubes. However, it is presently unknown whether BACE1 and the product of its activity, soluble APPβ (sAPPβ), contribute to lipid-induced inflammation and insulin resistance in skeletal muscle cells. Full-Text PDF