iTBS to Relieve Depression and Executive Dysfunction in Older Adults: An Open Label Study

The American Journal of Geriatric Psychiatry(2020)

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摘要
•What is the Primary Question addressed by this study?•This study examines the feasibility and tolerability of an intermittent Theta Burst Stimulation (iTBS) paradigm in older adults with depression and co-ocurrring executive dysfunction.•What is the Main finding of this study?•Older adults undergoing iTBS over bilateral dorso-lateral-prefrontal cortex experienced improvements in both depression and executive function.•Older adults with depression undergoing iTBS experienced noticeable reduction in problematic dysexecutive behaviors.•What is the meaning of the finding?•Our findings inform on the feasibility of this paradigm and advance the field towards testing neuromodulation treatments that target brain-networks affected in late life depression.
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关键词
Depression,older adults,late life depression,executive dysfunction,executive function,intermittent theta burst stimulation,transcranial magnetic stimulation,neuromodulation
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