Association of HLA genotypes with phenytoin induced severe cutaneous adverse drug reactions in Thai children.

Wiparat Manuyakorn,Plernpit Likkasittipan,Sukanya Wattanapokayakit,Supharat Suvichapanich,Wimala Inunchot,Nuanjun Wichukchinda, Chaiyos Khongkhatithuml,Lunliya Thampratankul,Wasu Kamchaisatian,Suwat Benjaponpitak,Surakameth Mahasirimongkol

Epilepsy Research（2020）

引用 12|浏览21

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摘要

•HLA-B*51:01 and HLA-C*14:02 are associated with PHT induced DRESS.•HLA-B*38:02 is associated with PHT induced SJS-TEN.•HLA-B*15:02 may not be associated with PHT induced SJS-TEN or DRESS in Thais.

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关键词

HLA-B*51:01,HLA-C*14:02,HLA-B*38:02,Phenytoin,Drug reaction

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