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Recombinant E rns -E2 protein vaccine formulated with MF59 and CPG-ODN promotes T cell immunity against bovine viral diarrhea virus infection.

Shenghua Wang,Guanghui Yang,Jiawei Nie,Renjie Yang,Mengze Du,Jinhui Su,Jing Wang,Jiufeng Wang,Yaohong Zhu

Vaccine（2020）

Cited 15|Views12
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Abstract
•The Erns, E2, or Erns-E2 protein vaccines containing MF59 and CPG-ODN being exploited.•Adjuvanted recombinant Erns-E2 protein vaccine producing higher antibody levels.•Adjuvanted recombinant Erns-E2 protein vaccine stimulating intense cellular immunity.•A subunit vaccine-adjuvant combination as a vaccine strategy to protect against BVDV.
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Key words
BVDV,Erns-E2 protein,Adjuvant,T-cell response,Anti-BVDV antibody,Viremia
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