Choice of first line systemic treatment in pancreatic cancer among national experts.

M Glatzer, D Horber,M Montemurro,R Winterhalder, R Inauen,M D Berger, B Pestalozzi, S Pederiva,M Pless,P M Putora

Pancreatology(2020)

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摘要
We identified multiple decision criteria relevant to all participating centers. We found consensus for the treatment of young (age below 65) patients with good performance status with FOLFIRINOX. For patients with increasing age and reducing performance status there was a decreasing trend to use gemcitabine + nab-paclitaxel. Gemcitabine monotherapy was typically offered to patients in the presence of comorbidities. For patients with ECOG 3-4, most of the experts recommended BSC.
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关键词
Pancreatic cancer,Treatment algorithm,Decision criteria,Nab-paclitaxel,FOLFIRINOX,decision-making
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