Outcomes of Pregnancy in Child A Liver Cirrhotic Patients: A Retrospective Multicenter Study

Only few studies reported the impact of Child A cirrhosis on pregnancy outcomes. Therefore, we aimed to assess the outcomes of pregnancy in Child A cirrhotic patients compared to noncirrhotic pregnant females in terms of maternal and neonatal outcomes. The present retrospective study was conducted from January 2013 till January 2018. Pregnant females with Child A cirrhosis and age and gestational age‐matched, noncirrhotic pregnant women were included. The main aim of this work was the differences in the pregnancy‐related outcomes between both studied groups. The present study included 100 pregnant cirrhotic women and 100 pregnant noncirrhotic women as a control group. In terms of the association between the presence of cirrhosis and maternal outcomes. The incidence of preeclampsia in the cirrhotic group was 6% in comparison to 2% in the noncirrhotic group ( P = .27). On the other hand, 35% of women in the cirrhosis group underwent cesarean section (CS) delivery compared to 20% only in the noncirrhotic group ( P = .018). Regarding neonatal outcomes, the incidence of preterm delivery and low birth weight were notably higher in the cirrhotic group than the noncirrhotic group (25% vs 7%, 15% vs 6% and P = .001, and 0.038). In contrary, there were no statistically significant variations between both groups in terms of stillbirth ( P = .72), small for gestational age ( P = .33), malformation ( P = .99), and neonatal death ( P = .99). Child A cirrhosis appears to increase the risks of prematurity, low birth weight and CS delivery; while it has no impact on maternal or neonatal mortality.