Deubiquitinase BRCC36 inhibits hypoxia-induced pulmonary arterial hypertension and remodeling

Hui Shen,Deshan Yao,Lina Zhang,Zhengang Zhang,Kaizheng Gong

Journal of Molecular and Cellular Cardiology（2020）

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摘要

We recently observed that deubiquitinase BRCC36 was involved in the negative regulation of transforming growth factor-β signaling. The present study aims to address the role of BRCC36 in hypoxia-induced pulmonary arterial hypertension (PAH) and remodeling.

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关键词

pulmonary arterial hypertension,hypoxia-induced

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