Pharmacogenetics of antiemetics for chemotherapy-induced nausea and vomiting: A systematic review and meta-analysis.

Astrid Eliasen,Kim Dalhoff,Rene Mathiasen,Kjeld Schmiegelow,Catherine Rechnitzer,Astrid Blicher Schelde,Dyah Aryani Perwitasari,Daiki Tsuji,Jesper Brok

Critical Reviews in Oncology/Hematology（2020）

引用 15|浏览29

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摘要

•Nausea and vomiting are common side effects of chemotherapy.•The severity of nausea and vomiting varies substantially among cancer patients.•Polymorphisms in ABCB1 and HTR3C are associated with the risk of nausea/vomiting.•The data on polymorphisms is still insufficient to allow clinical implementation.

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关键词

Neoplasms,Antineoplastic agents,Nausea,Vomiting,Antiemetics,Genetic polymorphism,Meta-analysis

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