Fungal Prophylaxis and Chronic Lung Allograft Dysfunction

There was no significant difference in freedom from CLAD at 3 years post-transplant for LTRs managed under a TAP versus UAP strategy or for these patients when grouped by discharge antifungal regimen. These results, while unexpected, pique interest in further investigation, particularly elucidating the relationship between prophylaxis and incidence of fungal colonization and invasive disease. Pursuing these avenues of study will advance our understanding of the utility and benefit of fungal prophylaxis in the LTR population.